منابع مشابه
Controlling flagellar strokes
he movements of cilia and flagella are driven by axonemal dynein ATPases, whose activity must be coordinated in space and time. On page 47, Rupp and Porter provide the first molecular characterization of a component of the dynein regulatory complex (DRC), a crucial but poorly understood regulator of flagellar movement. Besides suggesting a model for DRC assembly, the work identifies a possible ...
متن کاملCRIS—A Novel cAMP-Binding Protein Controlling Spermiogenesis and the Development of Flagellar Bending
The second messengers cAMP and cGMP activate their target proteins by binding to a conserved cyclic nucleotide-binding domain (CNBD). Here, we identify and characterize an entirely novel CNBD-containing protein called CRIS (cyclic nucleotide receptor involved in sperm function) that is unrelated to any of the other members of this protein family. CRIS is exclusively expressed in sperm precursor...
متن کاملProtein power strokes
How is dynamic instability regulated? Some microtubuleassociated proteins, or MAPs, can attach along the sides of the microtubules, slowing or reversing shrinkage. These MAPs are dominant in interphase cells and neurons, which is why microtubules in these cells are not very dynamic. Other MAPs, dominant in mitosis, attach to microtubule ends, where they can stabilize or destabilize microtubules...
متن کاملIschemic strokes in children.
Ischemic stroke is an uncommon, but significant cause of disability in childhood. Children with strokes present with predictable deficits as adults do; however, fever and seizures at stroke onset are more common in children than in adults. Strokes in children have diverse etiologies and require extensive evaluation. Etiology remains obscure in up to half of the patients. Prognosis in childhood ...
متن کاملWhy model strokes?
In this issue of Stroke, Professor Laszlo Molnar and coworkers describe another experimental model of stroke. An apparently reversible form of embolic intravascular occlusion may now be added to previous tabulations of various methods and outcomes. Professor Molnar and coworkers have previously validated their model by light microscopic criteria to show morphologic resemblance to ischemic patho...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2003
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1621iti3